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(c) To suggest to the Regional Office the calling of technical conferences and such additional work or investigation in health matters as in the opinion of the Regional Committee would promote the objective of the Organization within the region; (d) To co-operate with the respective regional committees of the United Nations and with those of other specialized agencies and with other regional international organizations having interests in common with the Organization; (<?) To tender advice, through the Director-General, to the Organization on international health matters which have wider than regional significance; (/) To recommend additional regional appropriations by the governments of the respective regions if the proportion of the central budget of the Organization allotted to that region is insufficient for the carrying out of the regional functions ; (g) Such other functions as may be delegated to the Regional Committee by the Health Assembly, the Board or the Director-General. Article Subject to the general authority of the Director-General of the Organization, the Regional Office shall be the administrative organ of the Regional Committee. It shall, in addition, carry out within the region the decisions of the Health Assembly and of the Board. Article 52 The head of the Regional Office shall be the Regional Director appointed by the Board in agreement with the Regional Committee. Article 53 The staff of the Regional Office shall be appointed in a manner to be determined by agreement between the Director-General and the Regional Director. Article 54 The Pan-American sanitary organization represented by the Pan-American Sanitary Bureau and the Pan-American Sanitary Conferences, and all other inter-governmental regional health organizations in existence prior to the date of signature of this Constitution, shall in due course be integrated with the Organization. This integration shall be effected as soon as practicable through common action based on mutual consent of the competent authorities expressed through the organizations concerned.